Saint-Ghislain covers 70.6 km² and has 23,311 inhabitants. The average age is 42, and 62% of residents own their dwelling. Average net income is €17,238 per person per year. The population is 52.1% women, with nationalities recorded as 90.8% Belgian, 4.3% Italian, 1.8% French, 0.8% Spanish, 0.4% American, 0.3% Moroccan, 0.2% German and 1.4% other. Houses make up 85.4% of the housing stock, compared with 14.6% apartment buildings. Building types include 30.2% open-type houses, farms and castles, 29.3% semi-closed houses, 23.2% closed houses, 14.1% apartment buildings, 2.4% commercial houses and 0.7% other types. The average building dates from 1941, and dwellings have about 5.7 rooms on average.
There are currently 0 houses for rent in the municipality, so no monthly rent range is listed; the supplied average monthly figure is €0. The A7 / E19–E42 is a 2-minute drive from the centre, while reaching the A8 / E429–E42 takes 32 minutes. Local main roads are the N50, N325, N524, N525 and N526. TEC buses serving Saint-Ghislain include line 100 from Ath, line 13 to Quevaucamps, line 14 from Mons, line 4 between Wasmes and Baudour, and line 7 between Quiévrain and Mons. The nearest stations to the centre are Saint-Ghislain, Boussu, Quaregnon, Hainin and Jemappes.
Childcare and education provision includes 13 nurseries, 26 nursery schools, 26 primary schools and 5 secondary schools. Examples named in the municipality are Groupe Scolaire Communal Fondamental De Tertre, Ecole Fondamental Libre La Sainte-Famille, Groupe Scolaire Communal De Sirault, Ecole Communale Jean-Rolland, Institut Saint-Joseph and Lycée Provincial D’Enseignement Technique Du Hainaut. Shopping choices include 2 Delhaize stores and 1 each of Louis Delhaize, Trafic, SPAR, Carrefour and Colruyt. There are no shared bicycles or shared cars in Saint-Ghislain, and no known charging station for electric vehicles. Brussels South Charleroi Airport can be reached in 30 minutes by car or 123 minutes by public transport.